Amlohab 5

Uses / indications

• Amlodipine 5 mg Tablet — Indications
• Amlodipine 5 mg is a calcium-channel blocker primarily indicated for:
• - Hypertension (high blood pressure) — used alone or with other antihypertensive medicines.
• - Chronic stable angina — helps prevent episodes of chest pain caused by reduced blood flow to the heart.
• - Vasospastic (Prinzmetal) angina — helps prevent coronary artery spasm–related chest pain.
• Usual adult starting dose for hypertension: 5 mg once daily, although dosing should be individualized by a doctor. Maximum commonly recommended dose is 10 mg once daily.
• Important: Amlodipine controls blood pressure and helps prevent angina; it is not used to immediately relieve an acute episode of chest pain.

Product information

AMLODIPINE 5 MG TABLETS
1. Composition
Each uncoated/film-coated tablet contains:
Amlodipine Besilate IP equivalent to Amlodipine 5 mg
Excipients: q.s.
2. Therapeutic Indications
Amlodipine is indicated for:
- Hypertension — alone or in combination with other antihypertensive agents.
- Chronic stable angina.
- Vasospastic (Prinzmetal's) angina.
- In appropriate patients with documented coronary artery disease. DailyMed
3. Dosage and Administration
Adults — Hypertension:
The usual initial dose is 5 mg once daily. Depending on the patient's response, the dose may be increased to a maximum of 10 mg once daily.
Elderly, small/fragile patients or patients with hepatic impairment:
A starting dose of 2.5 mg once daily may be considered.
Angina:
The recommended dose is generally 5–10 mg once daily.
Dosage should be individualized according to the patient's clinical response and blood-pressure target. Dose adjustments are generally made after allowing adequate time to assess the response. DailyMed
4. Method of Administration
- For oral administration.
- Take once daily, preferably at the same time each day.
- May be taken with or without food.
- Swallow the tablet with water.
- The medicine should be taken as prescribed and should not be discontinued abruptly without medical advice.
5. Contraindications
Amlodipine is contraindicated in patients with:
- Known hypersensitivity to amlodipine or any component of the formulation.
- Patients with a previous serious allergic reaction to amlodipine should not receive the medicine. DailyMed
6. Warnings and Precautions
Use with caution in:
- Severe hepatic impairment — dose titration should be gradual.
- Severe aortic stenosis, as symptomatic hypotension may occur.
- Patients with severe obstructive coronary artery disease, particularly when initiating treatment or increasing the dose, because worsening angina or acute myocardial infarction has been reported.
- Elderly patients, who may require lower starting doses. DailyMed
7. Common Adverse Effects
The most commonly reported adverse effect is:
- Peripheral edema (swelling of ankles/feet)
Other reported effects include:
- Headache
- Dizziness
- Flushing
- Fatigue
- Nausea
- Abdominal discomfort/pain
- Somnolence
- Palpitations
Peripheral edema tends to be dose-related. DailyMed
8. Drug Interactions
Amlodipine can be used with many other antihypertensive medicines, but the treating physician should review concomitant medications.
When amlodipine is used with simvastatin, the simvastatin dose should not exceed 20 mg daily according to the cited prescribing information. DailyMed
9. Pregnancy and Lactation
Use during pregnancy or breastfeeding should be based on medical advice after assessment of the potential benefits and risks.
10. Overdose
Overdose may result in excessive peripheral vasodilation, marked hypotension and potentially reflex tachycardia.
Patients with suspected overdose require immediate medical evaluation and supportive management.
11. Storage
Store in a cool, dry place, protected from light and moisture, and keep out of reach of children.